Edmonton police have laid second-degree murder charges against a man in connection to a homicide from September, that took place in the inner-city.

On Sept. 8, police were called to the area of 95 Street and 102 Avenue, a location known to police as one often visited by many in the inner-city who gather there and drink.

Officers found a man and a woman suffering from stab wounds in a nearby parking lot.

Both victims were transported to hospital, where the man died.

The 33-year-old woman survived.

Police say witness accounts, video surveillance, forensic evidence and help from an inner-city shelter led to the arrest of an Edmonton man, he was arrested without incident Thursday morning at a west end motel.

George Andrew Campbell, 51, has been charged with one count each of second-degree murder, aggravated assault and possession of an offensive weapon in the death of Douglas Gladue., 50

Police Chief Rod Knecht said in a press conference Friday that he doesn't often comment on individual homicide cases, but this case resonated with him.

"We always look at incidents like this and wonder if they were preventable, if there was something that could have been done to keep those people from drinking or gathering on the streets so late at night," Knecht said. "While we may never have the answers, we have been working with the community and social agencies to see if there is a better way we can come up with to support our vulnerable people and homeless citizens."

The Edmonton Police Service and CAT Deployment partners are working on strategies to find a better way to support the inner-city community on a 24-hour basis.